Content will range from basic protein structure and function to consideration of cell type-specific features and the consequences of diseaseassociated changes and potential therapeutic intervention. Of course this two-dimensional, albeit often colourful representation takes no account of the three-dimensional structure of a cell, the nature of the external and internal milieu, the dynamics of changes in protein levels and interactions, or the variations between cells in different tissues.Įach book in this series, entitled “Proteins and Cell Regulation”, will seek to explore specific protein families or categories of proteins from the viewpoint of the general and specific functions they provide and their involvement in the dynamic behaviour of a cell. The large diagrams of cells to be found on the walls of many a biologist’s office are usually adorned with parallel and interconnecting pathways linking the multitude of components and suggest a clear logic and understanding of the role played by each protein. Our knowledge of the ways in which a cell communicates with its environment and how it responds to information received has reached a level of almost bewildering complexity. Professor Jon Frampton Professor of Stem Cell Biology Institute for Biomedical Research, Birmingham University Medical School, Division of Immunity and Infection Birmingham United Kingdom Professor Anne Ridley Ludwig Institute for Cancer Research and Department of Biochemistry and Molecular Biology University College London London United Kingdom
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